Fibrosarcoma
Synopsis

Fibrosarcomas usually arise deep to the subcutis, from fascia, including within muscle, or from aponeuroses or tendons. In this location, they may become attached to or encircle underlying bone. Very rarely, they may arise from the subcutaneous tissue. Trauma, chronic scarring, and prior irradiation have been implicated as causative factors.
Many tumors that were previously classified as fibrosarcomas have recently been reclassified as other fibroblastic tumors. Therefore, prognostic data may not be reliable, and further contemporary studies are needed. After excision, local recurrence rates were reported to approach 60% but were reduced to 25% when postoperative radiation was used. The 5-year survival rate was reported to be 40%-60% in adults.
Metastases often arise within 2 years of diagnosis, but in histologically low-grade tumors, they may take many years to develop. The tumor metastasizes primarily to the lung and bone.
Related topic: infantile fibrosarcoma
Codes
C49.9 – Malignant neoplasm of connective and soft tissue, unspecified
SNOMEDCT:
443250000 – Malignant fibromatous neoplasm
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Last Updated:07/06/2021