Multinucleate cell angiohistiocytoma
Synopsis

Although the etiology is largely unknown, MCAs are thought to be reactive, with several case reports describing them arising in association with neoplasms, inflammatory processes, or trauma. Studies have also demonstrated a potential role of hormonal signaling, with increased expression of estrogen receptor alpha identified within MCAs. Some experts have also proposed that MCAs are on a spectrum of fibrohistiocytic proliferations that also includes dermatofibromas and fibrous papules, but this remains controversial.
Codes
D23.9 – Other benign neoplasm of skin, unspecified
SNOMEDCT:
21985009 – Fibrohistiocytic proliferation of the skin
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Last Updated:07/09/2020