CREST syndrome - Nail and Distal Digit
See also in: OverviewSynopsis
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Patients with lcSSc can be differentiated from those with dcSSc by the limited skin involvement to distal extremities. The anticentromere antibody, while only present in approximately 40% of individuals with lcSSc, is a laboratory test used to differentiate the two entities.
There is also a rare subtype of SSc that lacks skin sclerosis but has Raynaud phenomenon, nail fold capillary changes, internal organ involvement, and positive serologies called SSc sine scleroderma that has a similar trajectory to lcSSc.
Codes
M34.1 – CR(E)ST syndrome
SNOMEDCT:
31848007 – CREST syndrome
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Last Updated:04/11/2019
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